TITLE：Activatable Nanotheranostics for In Vivo Multimodality Imaging and Therapy
SPEAKER：Dr. Peng Huang, National Institute of Biomedical Imaging and Bioengineering (NIBIN), NIH, USA
TIME：10:00 am, January 13 (Tuesday), 2015
LOCATION： Room 526 (Lecture Hall), Chemistry Building A (化学A楼五楼演讲厅)
INVITER：朱新远教授（beat365）

Abstract：
     Activatable theranostics are novel clinical solutions for early recognition, diagnosis, monitoring, and prognosis of diseases by enhancing contrast in various imaging modalities followed by tailored therapy. So far, controllable activations by external stimuli such as light, temperature, pH, applied magnetic/electrical field, ultrasound, or enzymatic action, have been proposed as triggered theranostic systems. Light, typically a wavelength-selected laser, as an exogenous stimulus with the advantage of spatiotemporal selectivity, has been extensively employed for photothermal, photodynamic, and/or photo-triggered chemo/gene therapy. In the past few years, we have developed a series of photoactivatable theranostics that have shown excellent imaging and high efficacy of cancer therapy in animal experiments. This talk will highlight our recent advances in using photoresponsive nanoplatforms for in vivo multimodality imaging and imaging-guided therapy. Some issues of activatable theranostics in clinical translation will also be discussed.
Biography:
     Dr. Huang received his Ph.D. degree in Biomedical Engineering from the Shanghai Jiao Tong University, China in 2012. Then he joined the Laboratory for Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH) as a postdoctoral fellow. In the past few years, Dr. Huang has focused on the design, synthesis, and biomedical applications of functional nanomaterials. His research interests mainly include (1) Controlled synthesis methods of nanomaterials, (2) Self-assembly of functional nanomaterials for drug delivery, biological study, imaging and therapy, and (3) Development of activatable theranostics for tumor imaging and targeted therapy. Starting from 2008, Dr. Huang has authored over 70 peer-reviewed papers, many of which were published on top chemistry, materials and biomedicine journals: Adv. Mater., JACS, Angew. Chem. Int. Ed., PNAS, ACS Nano, Adv. Funct. Mater., Biomaterials, and so on (total citation > 1,900, H-index = 26). Recently, he won “Xiuwen Wang Memorial Award” for Outstanding Young Scientist, recognizing his outstanding research achievement as a postdoctoral fellow and exemplary support of the research community in NIH/NIBIB.