TOPIC:In Situ Super-resolution Imaging of Catalytic Reaction and Molecular Transport on Single Nanocatalysts
SPEAKER:Associate Professor Ning Fang, Georgia State University
TIME:May 23 (Monday)AM10:00
LOCATION:Room 518, Chemistry Building A (化学A楼518会议室)
INVITER: 任吉存 教授

Abstract：The emergence of single molecule-based super-localization and super-resolution microscopy imaging techniques have dramatically improved our ability to reveal more detailed molecular dynamics and structural information and led to new discoveries in chemical and biological research that were previously unattainable with conventional diffraction-limited techniques. However, the current super-resolution chemical imaging techniques still lack several critical abilities, including insufficient axial resolution and the difficulty of imaging more complex three-dimensional (3D) nanomaterials. In seeking to circumvent these limitations, we are developing 3D super-resolution imaging for understanding molecular dynamics (including diffusion, adsorption, and chemical conversion, as well as their coupling) in nanopores at the single-molecule level under operando conditions. Highly tunable core-shell structures with well-defined geometry and manageable complexity have been designed and synthesized, and then visualized under our optical imaging system. Single molecule trajectories with nanometer resolution have been acquired to elucidate the effects of pore size, length, orientation, and surface ligands on molecular transport. New experimental insights on transport in nanoscale confinement acquired with the model core-shell porous structures can be generalized to guide the development of porous materials for heterogeneous catalysis and analytical separations.

CV of NING FANG
Department of Chemistry, Georgia State University
Email: nfang@gsu.edu； Phone: 404-413-5513

APPOINTMENTS
07/2015 – Present Associate Professor, Department of Chemistry, Georgia State University
08/2008 – 05/2015 Assistant Professor, Department of Chemistry, Iowa State University
Faculty Scientist, Ames Laboratory, U.S. Department of Energy
PROFESSIONAL PREPARATION
08/2006 – 08/2008 Postdoctoral Fellow, Iowa State University and Ames Laboratory, U.S.
Department of Energy. Advisor: Dr. Edward S. Yeung
01/2003 – 08/2006 Ph.D., Analytical Chemistry, University of British Columbia, Canada
Advisor: Dr. David D.Y. Chen
08/1999 – 12/2002 M.S., Analytical Chemistry, University of British Columbia, Canada
Advisor: Dr. David D.Y. Chen
09/1994 – 07/1998 B.S., Xiamen University, China
Major in Chemistry, Minor in Computer Science

Selected Publications
1. Dong, B. ; Chen, Y. ; Zhu, S.; Bassham, D.C.; Fang, N.* Stochastic Optical Reconstruction Microscopy Imaging of Microtubule Arrays in Intact Arabidopsis thaliana Seedling Roots. Scientific Reports, doi: 10.1038/srep15694 (2015).
2. Han, R. ; Ha, J.W. ; Xiao, C.; Pei, Y.; Qi, Z.; Dong, B.; Huang, W.*; Fang, N.*   Geometry-assisted 3D Super-localization Imaging of Single Molecule Catalysis on Modular Multilayer Nanocatalysts. Angewandte Chemie International Edition, 53(47), 12865-1286 (2014).
3. Ha, J.W.; Ruberu, T.P.A.; Han, R.; Dong, B.; Vela, J.*; Fang, N.*   Super-resolution Mapping of Photo-generated Electron and Hole Separation in Single Metal-Semiconductor Nanocatalysts. Journal of the American Chemical Society, 136(4), 1398-1408 (2014).
4. Stender, A.S.; Marchuk, K.; Liu, C.; Sander, S.; Meyer, M.W.; Smith, E.A.; Neupane, B.; Wang, G.; Li, J.; Cheng, J.X.; Huang, B.; Fang, N.*   Single Cell Optical Imaging and Spectroscopy. Invited review for the April 2013 thematic issue on “New Frontiers in Bioanalytical Chemistry”. Chemical Reviews, 113(4), 2469-2527 (2013).
5. Gu, Y.; Sun, W. ; Wang, G.; Jeftinija, K.; Jeftinija S.; Fang, N.*   Rotational Dynamics of Cargos at Pauses during Axonal Transport. Nature Communications, 3, doi: 10.1038/ncomms2037 (2012).
6. Ha, J.W.; Marchuk, K.; Fang, N.*   Focused Orientation and Position Imaging (FOPI) of Single Anisotropic Plasmonic Nanoparticles by Total Internal Reflection Scattering Microscopy. Nano Letters, 12(8), 4282-4288 (2012).
7. Marchuk, K.; Guo, Y.; Sun, W.; Vela, J.; Fang, N.*   High-Precision Tracking with Non-Blinking Quantum Dots Resolves Nanoscale Vertical Displacement. Journal of the American Chemical Society, 134(14), 6108-6111 (2012).
8. Gu, Y.; Sun, W.; Wang, G.; Fang, N.* Single Particle Orientation and Rotation Tracking Discloses Distinctive Rotational Dynamics of Drug Delivery Vectors on Live Cell Membranes. Journal of the American Chemical Society, 133(15), 5720-5723 (2011).
9. Stender, A.S.; Wang, G.; Sun, W.; Fang, N.* Influence of Gold Nanorod Geometry on Optical Response. ACS Nano, 4(12), 7667–7675 (2010).
10. Wang, G.; Sun, W.; Luo, Y.; Fang, N.* Resolving Rotational Motions of Nano-objects in Engineered Environments and Live Cells with Gold Nanorod Probes and Differential Interference Contrast Microscopy. Journal of the American Chemical Society, 132(46), 16417–16422 (2010).