李明强助理研究员
电子邮件：limingqiang@sjtu.edu.cn
通讯地址：上海市东川路800号beat365A楼
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教育背景
2013年9月－2017年6月 上海理工大学 博士
2010年9月－2013年3月 上海理工大学 硕士
2006年9月－2010年7月 安阳师范学院 学士
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工作经历
2020.4 －至今 beat365 助理研究员
2017.11－2019.11 上海交通大学材料科学与工程学院 博士后
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研究方向
1）DNA计算与存储
2）DNA分子机器
3）人工智能及多尺度分子模拟应用
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科研项目
参加国家自然科学基金面上项目、国家科技支撑计划、上海市科学技术委员会科研计划项目。
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代表性论文专著
Liu, Y.; Dai, Z.; Xie, X.; Li, B.; Jia, S.; Li, Q.; Li, M. *; Fan, C.; Liu, X. * Spacer-Programmed Two-Dimensional DNA Origami Assembly. J. Am. Chem. Soc. 2024, 146 (8), 5461–5469. https://doi.org/10.1021/jacs.3c13180.
Li, C.; Xie, Y.; Cheng, X.; Xu, L.; Yao, G.; Li, Q.; Shen, J.; Fan, C. *; Li, M. * Single-Molecule Assessment of DNA Hybridization Kinetics on Dye-Loaded DNA Nanostructures. Small 2024, 1 (1), 2402870. https://doi.org/10.1002/smll.202402870.
Cao, N. #; Guo, R. #; Song, P.; Wang, S.; Liu, G.; Shi, J.; Wang, L.; Li, M.; Zuo, X.; Yang, X.; Fan, C.; Li, M. *; Zhang, Y. * DNA Framework–Programmed Nanoscale Enzyme Assemblies. Nano Lett. 2024, 24 (15), 4682–4690. https://doi.org/10.1021/acs.nanolett.4c01137.
Liu, Y. #; Li, B. #; Wang, F.; Li, Q.; Jia, S.; Liu, X.; Li, M. * Quantitative Analysis of Resistance to Deformation of the DNA Origami Framework Supported by Struts. ACS Appl. Bio Mater. 2024, 7 (2), 1311–1316. https://doi.org/10.1021/acsabm.3c01270.
Wang, H.; Li, Z.; Liu, X.; Jia, S.; Gao, Y. *; Li, M. * Rapid Silicification of a DNA Origami with Shape Fidelity. ACS Appl. Bio Mater. 2024, 7 (4), 2511–2518. https://doi.org/10.1021/acsabm.4c00124.
Sun, C.; Li, M. *; Wang, F. * Programming and Monitoring Surface-Confined DNA Computing. Bioorg. Chem. 2024, 143, 107080. https://doi.org/10.1016/j.bioorg.2023.107080.
Wei, X. #; Xu, H. #; Zhou, M.; Zhou, Q.; Li, M. *; Liu, Y. * Chemically Modified microRNA Delivery via DNA Tetrahedral Frameworks for Dental Pulp Regeneration. J. Nanobiotechnology 2024, 22 (1), 150. https://doi.org/10.1186/s12951-024-02393-9.
Chen, J. #; Gu, P. #; Ran, G. #; Zhang, Y. #; Li, M.; Chen, B.; Lu, H.; Han, Y.-Z.; Zhang, W.; Tang, Z.; Yan, Q.; Sun, R.; Fu, X.; Chen, G.; Shi, Z.; Wang, S.; Liu, X.; Li, J.; Wang, L.; Zhu, Y. *; Shen, J. *; Tang, B. Z. *; Fan, C. * Atomically Precise Photothermal Nanomachines. Nat. Mater. 2024, 23 (2), 271–280. https://doi.org/10.1038/s41563-023-01721-y.
Qi, M.; Ma, W.; Xu, Q.; Wang, F.; Song, P.; Jia, S.; Zuo, X.; Li, M. *; Yao, G. *; Fan, C. Meta-DNA Strand Displacement for Sub-Micron-Scale Autonomous Reconfiguration. J. Am. Chem. Soc. 2023, 145 (30), 16812–16820. https://doi.org/10.1021/jacs.3c04884.
Lv, H.; Xie, N.; Li, M.; Dong, M.; Sun, C.; Zhang, Q.; Zhao, L.; Li, J.; Zuo, X.; Chen, H.; Wang, F. *; Fan, C. * DNA-Based Programmable Gate Arrays for General-Purpose DNA Computing. Nature 2023, 622 (7982), 292–300. https://doi.org/10.1038/s41586-023-06484-9.
Zheng, H. #; Li, H. #; Li, M. #; Zhai, T.; Xie, X.; Li, C.; Jing, X.; Liang, C.; Li, Q.; Zuo, X.; Li, J.; Fan, J.; Shen, J.; Peng, X.; Fan, C. A Membrane Tension‐Responsive Mechanosensitive DNA Nanomachine. Angew. Chem. Int. Ed. 2023, 62 (35), e202305896. https://doi.org/10.1002/anie.202305896.
Hao, Y.#; Li, M. #; Zhang, Q.; Shi, J.; Li, J.; Li, Q.*; Fan, C. *; Wang, F. * DNA Origami‐Based Single‐Molecule CRISPR Machines for Spatially Resolved Searching. Angew. Chem. Int. Ed. 2022, 61 (34), e202205460. https://doi.org/10.1002/anie.202205460.
